• 6 Posts
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Joined 1 month ago
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Cake day: June 2nd, 2026

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  • Glad it helps you get by! I hadn’t heard of the rotating antihistamines trick and was curious about the mechanism, so I asked Dr. DuckDuckGo. Could’ve always been some other tolerance mechanism, like faster breakdown of the drug, which rotating might help with. The paper does mention benadryl and a handful of other substances, but it’s also ancient by research standards, so I don’t know if that applies to all antihistamines or if some circumvent tolerance induction somehow.


  • Does rotating them actually work? I thought they all just blocked your histamine receptors, so your body couldn’t care less just which substance did that for expressing more histamine receptors / making more histamine, thereby developing tolerance.

    Edit: Yeah, so I hate to place a nocebo here, but taking a break, not rotating them, seems to be the only effective remedy to anti-histamine tolerance. That is, if taking a break is tolerable, of course. I don’t know if that has to be said but please take medical advice from your health care professional of choice and not from a lemmy comment.

    Tolerance developed to one antihistamine extended to others, even though the chemical relationship was not close. Return of pharmacologic response to an antihistamine after discontinuance of the drug takes from 3 to 14 days.

    https://www.jacionline.org/article/0021-8707(51)90033-0/fulltext




  • Yes, but at least here I can choose an instance in a privacy friendly jurisdiction or one that is small enough, including a self-hosted one. It’s not a perfect shield, but federation helps a lot with digital independence (which is why it’s prominent in pre-internet theories of how to make anarchy work without collapsing into warlordism).


  • Spoiler alert, both British officials and EU officials are openly considering to slap an age restriction on VPN software, too. Would turn into a weird Catch-22, where you need a non-restricted VPN to download a non-restricted VPN, like in China right now.


  • tired_fedora@lemmy.mlOPtoPrivacy@lemmy.mlSo it begins
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    9 days ago

    Oh, I absolutely am blaming the politicians behind this (and the lobby groups behind them). The only strictly wrong thing Reddit does is how it implements that law, i.e., using third-party age verification that happens to also use your data to profile you and that has been shown to be insecure (Further Reading links in my post).


  • tired_fedora@lemmy.mlOPtoPrivacy@lemmy.mlSo it begins
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    9 days ago

    Agreed. Lemmy, while being very new, mimics features of ye olden times. Newsgroup era and all… But Reddit kinda started that way and then, as all good things, slowly enshittified. It seemed to resist enshittification longer than most sites. At least that was my impression. But good things can’t last. There’s no such thing as a free lunch, after all, I guess.








  • This is tragic and evil and another good reason to talk about intellectual property rights and ownership, but I am smirking a bit reading this article, as I can’t shake the feeling that Arnold Schwarzenegger paid for it. Two screenshots from Judgement Day, and a title card for the movie at the bottom of this article 🤭?

    Edit: bemusement about the Governator aside, I think this should be really straight forward to regulate. I remember the EU passing regulation a few years back that it only counts as a purchase online when you have to click something that clearly says “Purchase” or “pay now” and not, for example, click a nondescript link or “continue” button. IANAL but I could see similar regulation saying “if it’s called ‘buy’ or another term that implies permanent ownership, it must be permanent and can’t be revoked. Otherwise, the company must call it ‘rent’ or sth along those lines”.